Search results for "Carotid plaques"

showing 5 items of 5 documents

The size of juxtaluminal hypoechoic area in ultrasound images of asymptomatic carotid plaques predicts the occurrence of stroke

2013

Abstract OBJECTIVE: To test the hypothesis that the size of a juxtaluminal black (hypoechoic) area (JBA) in ultrasound images of asymptomatic carotid artery plaques predicts future ipsilateral ischemic stroke. METHODS: A JBA was defined as an area of pixels with a grayscale value 10 mm(2) (P 8 mm(2)) was still significant after adjusting for other plaque features known to be associated with increased risk, including stenosis, grayscale median, presence of discrete white areas without acoustic shadowing indicating neovascularization, plaque area, and history of contralateral TIA or stroke. Plaque area and grayscale median were not significant. Using the significant variables (stenosis, discr…

Asymptomatic carotid plaqueMaleTime Factorsmedicine.medical_treatmentCarotid endarterectomyKaplan-Meier EstimateSeverity of Illness Indexasymptomatic carotid artery stenosis; hypoecoic area; StrokeRisk FactorsCarotid StenosisUltrasonography Doppler ColorProspective cohort studyStrokeAged 80 and overNeovascularization Pathologichypoecoic areaMiddle AgedPrognosisPlaque AtheroscleroticEuropeStrokeIschemic Attack TransientPredictive value of testsFemaleRadiologymedicine.symptomjuxtaluminal hypoechoic area ultrasound images asymptomatic carotid plaques strokeCardiology and Cardiovascular MedicineCarotid Artery InternalAdultmedicine.medical_specialtyAsymptomaticRisk AssessmentAsymptomatic carotid plaque; Brain ischemia; Stroke; EchographyBrain ischemiaPredictive Value of Testsasymptomatic carotid artery stenosimedicineHumanscardiovascular diseasesAgedProportional Hazards Modelsbusiness.industryProportional hazards modelmedicine.diseaseAcoustic shadowSettore MED/11 - Malattie Dell'Apparato CardiovascolareStenosisROC CurveAsymptomatic DiseasesLinear ModelsSurgeryasymptomatic carotid artery stenosisEchographybusinessFollow-Up Studies
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Association Between Carotid Atherosclerosis and Metabolic Syndrome: Results From the ISMIR Study

2010

The metabolic syndrome (MetS) has previously been associated with an early marker of atherosclerosis, the carotid intima-media thickness (IMT). From the ISMIR (Ispessimento Medio Intimale e Rischio cardiovascolare [media-intima thickness and cardiovascular risk]) study population of 479 asymptomatic participants, we identified 80 participants with MetS. Carotid IMT and plaques were evaluated by ultrasonography. Blood samples were obtained from all participants. Participants with MetS had a significantly higher prevalence of a carotid IMT > 0.80 mm (P = .004) and of carotid plaques (P < .001) as compared with participants without MetS. Carotid IMT was significantly correlated with fas…

Blood GlucoseCarotid Artery DiseasesMalemedicine.medical_specialtycarotid intima-media thickness; carotid plaques; fibrinogen; metabolic syndrome; triglyceridescarotid intima-media thicknessFibrinogenAsymptomaticchemistry.chemical_compoundRisk FactorsInternal medicinemedicineHumanscardiovascular diseasesTriglyceridesAgedMetabolic SyndromeCreatinineVascular diseasebusiness.industrycarotid plaquesFibrinogenMiddle Agedmedicine.diseaseUric AcidCross-Sectional Studiesmedicine.anatomical_structureEndocrinologyItalychemistryCreatininecardiovascular systemCardiologyUric acidPopulation studyFemalemedicine.symptomMetabolic syndromeTunica IntimaTunica MediaCardiology and Cardiovascular Medicinebusinessmedicine.drugArteryAngiology
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Naïve hepatitis B e antigen-negative chronic hepatitis B patients are at risk of carotid atherosclerosis: A prospective study

2021

BACKGROUND There is an increased risk of atherosclerosis in patients with chronic hepatitis C or human immunodeficiency virus, but there is scarce data on hepatitis B virus infection. The hypothesis of this study is that hepatitis B virus infection increases the risk of carotid plaques and subclinical atherosclerosis in naïve hepatitis B e antigen (HBeAg) negative subjects. AIM To assess the rate of carotid plaques and subclinical atherosclerosis in naïve HBeAg negative subjects in comparison with a cohort of healthy controls. METHODS Prospective case-control collaborative study conducted in two tertiary hospitals. Four hundred and two subjects prospectively recruited at the outpatient clin…

Carotid Artery DiseasesHepatitis B virusmedicine.medical_specialtyIntima-media thicknessCardiovascular risk Carotid plaques Endothelial dysfunction Hepatitis B virus Intima-media thickness Subclinical atherosclerosis Carotid Intima-Media Thickness Hepatitis B e Antigens Humans Prospective Studies Carotid Artery Diseases Hepatitis B Chronicmedicine.disease_causeCarotid Intima-Media ThicknessGastroenterologyHepatitis B ChronicInternal medicinemedicineHumansOutpatient clinicCarotid plaquesSubclinical atherosclerosisEndothelial dysfunctionHepatitis B e AntigensProspective StudiesRisk factorProspective cohort studyHepatitis B virusbusiness.industryGastroenterologyGeneral MedicineOdds ratioHepatitis BCardiovascular riskmedicine.diseaseIntima-media thicknessHBeAgProspective StudybusinessWorld Journal of Gastroenterology
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Expression of inflammation-related genes in human atherosclerotic plaques

2010

Aims: Atherosclerosis is an inflammator y disease which molecular mechanisms are not been completely investigated. Our aim is to perform a wide expression study of inflammation related genes in human atherosclerotic plaques. Methods: The Human Inflammation Array (Applied Biosystems) was used to perform the mRNA quantification of 92 inflammation-related genes in 12 atherosclerotic plaques, their respective adjacent regions (with a lower grade lesion) and 7 healthy ar teries. The principle of the array is the real-time PCR amplification with a TaqMan probe specific for each gene. Data analysis was performed with SDS 2.3 software with the comparative Ct method using the gene beta-2-microglobulin as h…

atherosclerosis carotid plaques mRNASettore MED/22 - Chirurgia Vascolare
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EFFECT OF IMAGE NORMALIZATION ON CAROTID PLAQUE CLASSIFICATION AND THE RISK OF IPSILATERAL HEMISFERIC ISCHEMIC EVENTS. RESULTS FROM THE ASYMPTOMATIC …

2005

The aim of this study was to determine the effect of image normalization on plaque classification and the risk of ipsilateral ischemic neurologic events in patients with asymptomatic carotid stenosis. The first 1,115 patients recruited to the Asymptomatic Carotid Stenosis and Risk of Stroke (ACSRS) study with a follow-up of 6 to 84 months (mean 37.1 months) were included in this study. Duplex ultrasonography was used for grading the degree of internal carotid artery stenosis and for plaque characterization (types 1-5), which was performed before and after image normalization. One hundred sixteen ipsilateral ischemic hemispheric events occurred. Image normalization resulted in 60% of plaques…

carotid plaques classification image normalization ultrasound
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